Pathophysiological and clinical aspects of combat anticholinesterase poisoning.

2, 4-D Dichlorophenoxyacetic Acid Poisoning; Case Report and Literature Review

Background: 2, 4-dichlorophenoxyacetic acid, (2, 4-D) is a selective herbicide available as the acids, esters and several salts which vary in their chemical properties, environmental behaviour, and to a lesser extent toxicity. The salt and ester forms are derivatives of the parent acid. It is widely used as a weed killer. The 2, 4-D dimethylamine is one of the salts of this group. Case Presenta...

Plasma concentrations of the oxime Pralidoxime Mesylate (P2S) after repeated oral and intramuscular administration.

The use of the oxime P2S as intravenous therapy for organophosphorus anticholinesterase poisoning is well known. In emergency situations this route of administration may prove impractical due to severe symptoms of anticholinesterase poisoning and therefore the intramuscular route is to be preferred. The absolute intramuscular dose of P2S per man, recommended as necessary for adequate therapy of...

Presentation and outcome of severe anticholinesterase insecticide poisoning.

AIMS To document the patterns of presentation and outcome of severe anticholinesterase insecticide poisoning in children requiring intensive care. METHODS Retrospective case note review of all 5541 children admitted to the paediatric intensive care unit (PICU) of a university hospital during the 10 years from January 1990 to May 2000. Fifty four children (1%) with anticholinesterase insectici...

Health Aspects of Organophosphorous Pesticides in Asian Countries

Organophosphorous (OP) pesticides are used frequently in agriculture, particularly in Asian countries over the past decades. Poisoning by these agents, either as acute or chronic in these nations, is a serious health problem. OP pesticides residue in fruits and vegetables that may not induce early clinical features, could also affect the human health. Therefore, medical and health professionals...

The manifestations and treatment of poisoning due to nerve gas and other organic phosphate anticholinesterase compounds.